Crop Protection Products and Endocrine Testing

ENDOCRINETESTINGCrop protection products are among the most tested and regulated chemicals in the world – in fact, more tests are required for them than for pharmaceuticals. Crop protection products are extensively tested for potential adverse effects on living beings and ecosystems in studies mandated by national regulations, which include the evaluation of endocrine systems. Approvals are granted only when there is reasonable certainty that potential exposures will not cause adverse effects.

Data on all crop protection products required by regulatory authorities ensures human and environmental safety. A weight of evidence approach is used to evaluate every product for the potential to cause adverse effects as a result of endocrine activity and to determine the exposures at which no adverse effects are observed.

Crop protection products are evaluated for potential adverse effects on reproduction and development. Testing includes multi-generation reproduction studies in laboratory animals that assess potential impacts throughout life during two generations of offspring. These studies are conducted at extremely high doses – levels to which humans and wildlife species will not be exposed. In fact, human exposure to crop protection products is orders of magnitude lower than exposure to common, natural and more potent endocrine active substances like sugar, caffeine and soy protein.

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What is the Endocrine System?

The endocrine system is a set of glands that produce hormones throughout the body, regulating growth, development, metabolism, tissue and sexual function, mood, sleep, behavior and the body's internal environment.